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Enzyme-guided crystal growing surface-enhanced Raman scattering active Core/shell for bisphenol A detection

Abstract

Herein, a universal surface-enhanced Raman scattering (SERS) detection platform based on enzyme-guided crystal growth has been fabricated for the first time. In this system, BPA-aptamer-modified enzyme glucose oxidase was mixed with the complementary DNA sequences of the BPA-aptamer-coated AuNSs, leading to the reduction in crystallization rate to form the Core/shell and the SERS signal. Because of the different concentrations of the BPA target, the crystallization degree onto the AuNSs surface varied which led to the corresponding SERS signals. Our results showed that this method allowed a limit of detection of 5×10−17g mL−1 for BPA. This work opens a new horizon for constructing promising SERS sensors for environmental monitoring and food safety.

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Publication details

The article was received on 01 Dec 2017, accepted on 28 Jun 2018 and first published on 03 Jul 2018


Article type: Paper
DOI: 10.1039/C7AY02776A
Citation: Anal. Methods, 2018, Accepted Manuscript
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    Enzyme-guided crystal growing surface-enhanced Raman scattering active Core/shell for bisphenol A detection

    Z. Xu, R. Wang, B. Mei, L. Ding, L. Wang, M. Chen and Y. Cheng, Anal. Methods, 2018, Accepted Manuscript , DOI: 10.1039/C7AY02776A

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