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AIE active piperazine appended naphthalimide-BODIPYs: photophysical properties and applications in live cell lysosomal tracking

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Abstract

Piperazine appended naphthalimide-BODIPYs (NPB1–NPB4) exhibiting solvatochromism and aggregation-induced emission with a large Stokes shift (up to 146 nm) have been described. Separation of naphthalimide and BODIPY fluorophores by piperazine in these conjugates creates a donor–acceptor system and induces twisted intramolecular charge transfer, in addition to photoinduced electron transfer. The crucial role of naphthalimide, the alkyl chain length, the piperazine ring, and the solid-state packing on AIE has been extensively investigated by various studies. Superior cell permeability coupled with bio-compatibility of these conjugates offers a unique opportunity for their potential applications in live cell lysosomal tracking.

Graphical abstract: AIE active piperazine appended naphthalimide-BODIPYs: photophysical properties and applications in live cell lysosomal tracking

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Publication details

The article was received on 24 Jul 2018, accepted on 07 Oct 2018 and first published on 15 Oct 2018


Article type: Paper
DOI: 10.1039/C8AN01390J
Citation: Analyst, 2018, Advance Article
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    AIE active piperazine appended naphthalimide-BODIPYs: photophysical properties and applications in live cell lysosomal tracking

    B. K. Dwivedi, R. S. Singh, A. Ali, V. Sharma, S. M. Mobin and D. S. Pandey, Analyst, 2018, Advance Article , DOI: 10.1039/C8AN01390J

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