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Issue 19, 2018
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Lipid metabolism in inflammation-related diseases

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Abstract

There are thousands of lipid species existing in cells, which belong to eight different categories. Lipids are the essential building blocks of cells. Recent studies have started to unveil the important functions of lipids in regulating cell metabolism. However, we are still at a very early stage in fully understanding the physiological and pathological functions of lipids. The application of lipidomics for studying lipid metabolism can provide a direct readout of the cellular status and broadens our understanding of the mechanisms that underpin metabolic disease states. This review provides an introduction to lipid metabolism and its role in modulating homeostasis and immunity. We also describe representative applications of lipidomics for studying lipid metabolism in inflammation-related diseases.

Graphical abstract: Lipid metabolism in inflammation-related diseases

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Publication details

The article was received on 06 Jun 2018, accepted on 24 Jul 2018 and first published on 21 Aug 2018


Article type: Minireview
DOI: 10.1039/C8AN01046C
Analyst, 2018,143, 4526-4536

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    Lipid metabolism in inflammation-related diseases

    C. Zhang, K. Wang, L. Yang, R. Liu, Y. Chu, X. Qin, P. Yang and H. Yu, Analyst, 2018, 143, 4526
    DOI: 10.1039/C8AN01046C

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