Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 21st October 2020 from 07:00 AM to 07:00 PM (BST).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 10, 2018
Previous Article Next Article

Droplet microfluidic SANS

Author affiliations

Abstract

The coupling of droplet microfluidics and Small Angle Neutron Scattering (SANS) is demonstrated with a range of model systems: isotopic solvent (H2O/D2O) mixtures, surfactant (sodium dodecyl sulfate, SDS) solutions and colloidal (silica) suspensions. Several droplet carrier phases are evaluated and fluorinated oil emerges as a suitable fluid with minimal neutron background scattering (commensurate with air), and excellent interfacial properties. The combined effects of flow dispersion and compositional averaging caused by the neutron beam footprint are evaluated in both continuous and droplet flows and an operational window is established. Systematic droplet-SANS dilution measurements of colloidal silica suspensions enable unprecedented quantification of form and structure factors, osmotic compressibility, enhanced by constrained global data fits. Contrast variation measurements with over 100 data points are readily carried out in 10–20 min timescales, and validated for colloidal silica of two sizes, in both continuous and droplet flows. While droplet microfluidics is established as an attractive platform for SANS, the compositional averaging imposed by large (∼1 cm) beam footprints can, under certain circumstances, make single phase, continuous flow a preferable option for low scattering systems. We propose simple guidelines to assess the suitability of either approach based on well-defined system parameters.

Graphical abstract: Droplet microfluidic SANS

Back to tab navigation

Supplementary files

Article information


Submitted
11 Dec 2017
Accepted
15 Jan 2018
First published
16 Jan 2018

Soft Matter, 2018,14, 1759-1770
Article type
Paper

Droplet microfluidic SANS

M. Adamo, A. S. Poulos, C. G. Lopez, A. Martel, L. Porcar and J. T. Cabral, Soft Matter, 2018, 14, 1759
DOI: 10.1039/C7SM02433A

Social activity

Search articles by author

Spotlight

Advertisements