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Issue 22, 2018, Issue in Progress
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Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

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Abstract

A simple and efficient metal-free arylation of imidazo[1,2-a]pyridines at the C-3 position with arylhydrazine has been achieved at room temperature under ambient air conditions. Various 2,3-disubstituted imidazopyridines and imidazothiazoles were synthesized with high yields. The present methodology demonstrates the usefulness of commercially available aryl hydrazine as an arylating agent.

Graphical abstract: Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

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Supplementary files

Article information


Submitted
16 Feb 2018
Accepted
19 Mar 2018
First published
03 Apr 2018

This article is Open Access

RSC Adv., 2018,8, 12360-12367
Article type
Paper

Metal-free C–H arylation of imidazoheterocycles with aryl hydrazines

S. Jana, S. Samanta, A. K. Bagdi, V. Z. Shirinian and A. Hajra, RSC Adv., 2018, 8, 12360
DOI: 10.1039/C8RA01474D

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