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Issue 19, 2018

In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product

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Abstract

A new bilirubin oxidation end product (BOX) was isolated and characterized. The formation of the so-called Z-BOX C proceeds from bilirubin via propentdyopents as intermediates. This BOX was detected in pathological human bile samples using liquid chromatography/mass spectrometry and has potential relevance for liver dysfunction and cerebral vasospasms.

Graphical abstract: In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product

Supplementary files

Article information


Submitted
19 Jan 2018
Accepted
01 Mar 2018
First published
01 Mar 2018

Org. Biomol. Chem., 2018,16, 3553-3555
Article type
Communication

In vivo and in vitro identification of Z-BOX C – a new bilirubin oxidation end product

M. Ritter, S. Neupane, R. A. Seidel, C. Steinbeck and G. Pohnert, Org. Biomol. Chem., 2018, 16, 3553 DOI: 10.1039/C8OB00164B

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