Issue 20, 2018

4-Cyanopyridine-catalyzed anti-Markovnikov selective hydroboration of alkenes

Abstract

A highly selective anti-Markovnikov hydroboration reaction of alkenes with bis(pinacolato)diboron catalyzed by 4-cyanopyridine has been described. This strategy provides an efficient, practical and environmentally benign protocol for the construction of alkylboronates in moderate to good yields under metal-free conditions. A radical mechanism proceeding via a 4-cyanopyridine-ligated boryl radical was proposed.

Graphical abstract: 4-Cyanopyridine-catalyzed anti-Markovnikov selective hydroboration of alkenes

Supplementary files

Article information

Article type
Letter
Submitted
28 Jun 2018
Accepted
15 Sep 2018
First published
17 Sep 2018

New J. Chem., 2018,42, 16456-16459

4-Cyanopyridine-catalyzed anti-Markovnikov selective hydroboration of alkenes

R. Xu, G. Lu and C. Cai, New J. Chem., 2018, 42, 16456 DOI: 10.1039/C8NJ03222J

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