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Issue 15, 2018
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Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

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Abstract

Ciprofloxacin has been shown to exhibit potent herbicidal activity through action against plant DNA gyrase, presenting a novel mode of action. Analogues of ciprofloxacin have been prepared with increased herbicidal activity and diminished antibacterial activity, compared to ciprofloxacin, as demonstrated using model systems.

Graphical abstract: Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

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Supplementary files

Article information


Submitted
12 Dec 2017
Accepted
24 Jan 2018
First published
25 Jan 2018

Chem. Commun., 2018,54, 1869-1872
Article type
Communication

Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

M. D. Wallace, N. F. Waraich, A. W. Debowski, M. G. Corral, A. Maxwell, J. S. Mylne and K. A. Stubbs, Chem. Commun., 2018, 54, 1869
DOI: 10.1039/C7CC09518J

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