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Issue 72, 2018
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An active DNA-based nanoprobe for photoacoustic pH imaging

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Abstract

We report an active DNA construct capable of probing pH through a photoacoustic (PA) ratiometric analysis approach. Our nanoprobe enables different PA readout in tissue mimicking phantoms in the range between pH 6.8 to 7.8 at physiologically relevant sodium concentrations. Thus, it represents a promising platform to probe pH values relevant to the tumor microenvironment using PA.

Graphical abstract: An active DNA-based nanoprobe for photoacoustic pH imaging

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Supplementary files

Article information


Submitted
19 May 2018
Accepted
11 Jul 2018
First published
23 Aug 2018

This article is Open Access

Chem. Commun., 2018,54, 10176-10178
Article type
Communication

An active DNA-based nanoprobe for photoacoustic pH imaging

K. N. Baumann, A. C. Fux, J. Joseph, S. E. Bohndiek and S. Hernández-Ainsa, Chem. Commun., 2018, 54, 10176
DOI: 10.1039/C8CC04007A

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