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Issue 42, 2018
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Platinum(IV) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

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Abstract

Platinum(IV) prodrugs of clinically used cisplatin and oxaliplatin with two axial long lipid chains were developed for nanoparticle delivery to combat cisplatin resistance.

Graphical abstract: Platinum(iv) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

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Publication details

The article was received on 09 Apr 2018, accepted on 30 Apr 2018 and first published on 01 May 2018


Article type: Communication
DOI: 10.1039/C8CC02791A
Chem. Commun., 2018,54, 5369-5372

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    Platinum(IV) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

    Q. Chen, Y. Yang, X. Lin, W. Ma, G. Chen, W. Li, X. Wang and Z. Yu, Chem. Commun., 2018, 54, 5369
    DOI: 10.1039/C8CC02791A

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