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Issue 9, 2018
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A facile one-pot synthesis of acrylated hyaluronic acid

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Abstract

The synthesis of acrylated hyaluronic acid (HA-A) normally requires 2 to 3 steps of modification, needs laborious purification and also increases the risks of HA degradation. Here, we report that the conjugation of acrylate groups to hyaluronic acid can be successfully achieved via a new facile one-pot approach. Two types of new HA-A hydrogels (via chemical or UV crosslinking) were developed and applied for 3D cell encapsulation.

Graphical abstract: A facile one-pot synthesis of acrylated hyaluronic acid

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Article information


Submitted
09 Nov 2017
Accepted
20 Dec 2017
First published
20 Dec 2017

Chem. Commun., 2018,54, 1081-1084
Article type
Communication

A facile one-pot synthesis of acrylated hyaluronic acid

S. A, Q. Xu, P. McMichael, Y. Gao, X. Li, X. Wang, U. Greiser, D. Zhou and W. Wang, Chem. Commun., 2018, 54, 1081
DOI: 10.1039/C7CC08648B

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