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Issue 15, 2018
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Channel current analysis estimates the pore-formation and the penetration of transmembrane peptides

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Abstract

We measured the current signal of the transmembrane model peptides using the barrel-stave, toroidal pore, and penetration models in order to establish a precise assignment of the channel signals. In addition, we analyzed the spike signals to estimate the membrane penetration of model cell-penetration peptides of different lengths.

Graphical abstract: Channel current analysis estimates the pore-formation and the penetration of transmembrane peptides

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Article information


Submitted
07 Feb 2018
Accepted
28 Apr 2018
First published
02 May 2018

Analyst, 2018,143, 3540-3543
Article type
Communication

Channel current analysis estimates the pore-formation and the penetration of transmembrane peptides

Y. Sekiya, S. Sakashita, K. Shimizu, K. Usui and R. Kawano, Analyst, 2018, 143, 3540
DOI: 10.1039/C8AN00243F

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