Issue 88, 2017, Issue in Progress

Photo-triggered enzymatic degradation of biodegradable polymers


A material whose enzymatic degradation is initiated by an external stimulus is of great importance from the viewpoint of practical biodegradable polymers. In this context, we developed a method that controls the initiation of enzymatic degradation by light. 4,4′-Didecyloxy-3-methylazobenzene (Azo), which melts upon exposure to UV radiation, was coated onto biodegradable poly(L-lactide) and the enzymatic degradation of the polymer by proteinase K was successfully initiated and controlled by tuning the solid–liquid transition of the azo-based compound. This stimulus-triggered enzymatic degradation is a significant contribution to the development of lifetime-controlled biodegradable materials.

Graphical abstract: Photo-triggered enzymatic degradation of biodegradable polymers

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Article information

Article type
25 Sep 2017
01 Dec 2017
First published
08 Dec 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 55720-55724

Photo-triggered enzymatic degradation of biodegradable polymers

Y. Kikkawa, S. Tanaka and Y. Norikane, RSC Adv., 2017, 7, 55720 DOI: 10.1039/C7RA10598C

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