A flower-like NiO–SnO2 nanocomposite and its non-enzymatic catalysis of glucose
A flower-like NiO–SnO2 nanocomposite (NSNF) with electrochemical activity was synthesized by a solvothermal method. The morphology and composition of the NSNF have been characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM) and X-ray diffraction (XRD). The synthesized NSNF was immobilized onto the surface of an indium tin oxide (ITO) electrode and exhibited highly non-enzymatic catalysis towards the oxidation of glucose. The effect of NaOH concentration on the oxidation performance of glucose was investigated. Under the optimum conditions, the catalytic current showed a linear relationship with the increase of glucose concentration in the range of 0.01–26 mM, with a detection limit of 1 μM. The excellent sensing performance can be attributed to the unique porous architecture of NSNF, which enhanced the electron transfer during the electrochemical sensing of glucose. The glucose sensor also had a high selectivity for glucose detection, which could effectively resist the interference from ascorbic acid (AA), uric acid (UA), citric acid (CA), hydrogen peroxide (H2O2) and even other carbohydrates, such as fructose, sucrose and maltose. Finally, the glucose sensor was also used for glucose detection in real human serum samples and the results were satisfactory.