Issue 39, 2017

Total synthesis of natural products containing benzofuran rings


Research on natural products containing benzofuran has remarkably increased during the past few decades. Newly isolated natural products with complex structures are being studied, characterized and screened for possible biological activities. Several of such compounds have exhibited various biological activities, thus their total syntheses have attracted much attention from synthetic organic chemists. In this review, we aim to highlight the origins, structures, biological potencies, and synthetic approaches of those natural products bearing at least one benzofuran in their complex structures. Furthermore, we especially focus on the step in which this key heterocycle is installed during the total synthesis of a natural product as the desired target.

Graphical abstract: Total synthesis of natural products containing benzofuran rings

Article information

Article type
Review Article
27 Mar 2017
26 Apr 2017
First published
05 May 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 24470-24521

Total synthesis of natural products containing benzofuran rings

Majid M. Heravi, V. Zadsirjan, H. Hamidi and P. H. Tabar Amiri, RSC Adv., 2017, 7, 24470 DOI: 10.1039/C7RA03551A

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