A novel and simple solvent-dependent fluorescent probe based on a click generated 8-aminoquinoline–steroid conjugate for multi-detection of Cu(ii), oxalate and pyrophosphate

Abstract

In this work, a novel and simple deoxycholic acid-based fluorescent probe for solvent-dependent multi-detection of Cu²⁺, C₂O₄²⁻ and P₂O₇⁴⁻ has been facilely constructed by click chemistry. This probe displayed sensitive recognition toward Cu²⁺ in low-water-content CH₃CN aqueous solution (CH₃CN–H₂O, 99/1, v/v) via strong fluorescence quenching. Whereas, in DMSO–H₂O medium (1/1, v/v), it exhibited significant fluorescent enhancement for C₂O₄²⁻ and P₂O₇⁴⁻ over a wide range of tested anions. Moreover, with low detection limits and fast response time, the developed fluorescent molecule was used successfully for analysis of the target ions on test paper strips and in water samples.