Issue 7, 2017
From the journal:

RSC Advances

Bio-inspired enantioselective full transamination using readily available cyclodextrin†‡

Shiqi Zhang,a   Guangxun Li,b   Hongxin Liu,b   Yingwei Wang,a   Yuan Cao,a   Gang Zhao*a  and  Zhuo Tang ORCID logo *b  

* Corresponding authors

a School of Chemical Engineering, Sichuan University, Sichuan 610065, China
E-mail: gzhao@scu.edu.cn

b Natural Products Research Center, Chengdu Institution of Biology, Chinese Academy of Science, Chengdu, Sichuan 610041, China
E-mail: tangzhuo@cib.ac.cn

Abstract

The mimics of vitamin B6-dependent enzymes that catalyzed an enantioselective full transamination in the pure aqueous phase have been realized for the first time through the establishment of a new “pyridoxal 5′-phosphate (PLP) catalyzed non-covalent cyclodextrin (CD)-keto acid inclusion complexes” system, and various optically active amino acids have been obtained.

Graphical abstract: Bio-inspired enantioselective full transamination using readily available cyclodextrin

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Article information

DOI
https://doi.org/10.1039/C6RA27525G
Article type
Paper
Submitted
29 Nov 2016
Accepted
20 Dec 2016
First published
16 Jan 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 4203-4208

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Bio-inspired enantioselective full transamination using readily available cyclodextrin

S. Zhang, G. Li, H. Liu, Y. Wang, Y. Cao, G. Zhao and Z. Tang, RSC Adv., 2017, 7, 4203 DOI: 10.1039/C6RA27525G

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