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Issue 3, 2017
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AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

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Abstract

Aggregation-induced emission luminogens (AIEgens), tetraphenylethene, were post grafted onto mesoporous silica nanoparticles to form AIEgen-functionalised mesoporous materials. The obtained blue-emitting materials can serve as a fluorescence resonance energy transfer (FRET) donor for monitoring the release process of doxorubicin hydrochloride (DOX) as an acceptor by the change of the fluorescent signal, showing potential application in imaging-guided therapy.

Graphical abstract: AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

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Supplementary files

Article information


Submitted
07 Nov 2016
Accepted
31 Dec 2016
First published
03 Jan 2017

Inorg. Chem. Front., 2017,4, 468-472
Article type
Research Article

AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

D. Wang, J. Chen, L. Ren, Q. Li, D. Li and J. Yu, Inorg. Chem. Front., 2017, 4, 468 DOI: 10.1039/C6QI00488A

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