AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Mengxia Gao; Yuning Hong; Bin Chen; Yinan Wang; Wenjun Zhou; Wallace W. H. Wong; Jian Zhou; Trevor A. Smith; Zujin Zhao

doi:10.1039/C7PY00564D

AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Mengxia Gao,^a Yuning Hong,^b^c Bin Chen,^d Yinan Wang,^a Wenjun Zhou,^a Wallace W. H. Wong,^b Jian Zhou,*^a^b Trevor A. Smith*^b and Zujin Zhao*^d

Author affiliations

* Corresponding authors

^a College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou 310036, China
E-mail: zhoujian@hznu.edu.cn

^b School of Chemistry, The University of Melbourne, Australia
E-mail: trevoras@unimelb.edu.au

^c Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Australia

^d State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou 510640, China
E-mail: mszjzhao@scut.edu.cn

Abstract

A series of new conjugated polyelectrolytes (CPEs) containing tetraphenylethene units are synthesized and characterized. They show apparent aggregation-induced emission (AIE) characteristics and give fluorescence covering from cyan to red with high emission efficiencies in aggregates. These AIE CPEs can directly enter and stain living cells for fluorescence imaging with low cytotoxicity, and can provide information on cellular viscosity at different locations based on fluorescence lifetime imaging.

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Publication details

The article was received on 04 Apr 2017, accepted on 01 Jun 2017 and first published on 05 Jun 2017

Article type: Communication

DOI: 10.1039/C7PY00564D

Citation: Polym. Chem., 2017,8, 3862-3866

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AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

M. Gao, Y. Hong, B. Chen, Y. Wang, W. Zhou, W. W. H. Wong, J. Zhou, T. A. Smith and Z. Zhao, Polym. Chem., 2017, 8, 3862
DOI: 10.1039/C7PY00564D
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Mengxia Gao

Yuning Hong

Bin Chen

Yinan Wang

Wenjun Zhou

Wallace W. H. Wong

Jian Zhou

Trevor A. Smith

Zujin Zhao

Polymer Chemistry

AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

Abstract

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AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells

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