Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 8, 2017
Previous Article Next Article

Surfactant-free RAFT emulsion polymerization using a novel biocompatible thermoresponsive polymer

Author affiliations

Abstract

Thermoresponsive polymers have recently attracted considerable interest as macromolecular chain transfer agents in RAFT emulsion polymerizations to prepare nanoparticles with tuneable cores, sizes, shapes or surfaces. So far, this synthesis technique requires the use of a conventional surfactant as a stabilizer (e.g., sodium dodecyl sulphate), thus limiting its scope and potential applications. Here, we report the surfactant-free RAFT emulsion polymerization using, for the first time, a biocompatible thermoresponsive polymer as a dual macromolecular chain transfer agent and a macromolecular stabilizer. By randomly incorporating a hydrophilic component with ∼21 ethylene glycol units on the side chain, we synthesized a series of novel thermoresponsive copolymers that can form self-stabilized particles upon heating above their cloud point temperatures. These novel thermoresponsive copolymers have been successfully used to produce nanoparticles with tuneable shapes and cores, paving the way for the high-scale synthesis of biocompatible nanoparticles with complex nanostructures and tailored properties.

Graphical abstract: Surfactant-free RAFT emulsion polymerization using a novel biocompatible thermoresponsive polymer

Back to tab navigation

Supplementary files

Article information


Submitted
14 Dec 2016
Accepted
17 Jan 2017
First published
19 Jan 2017

Polym. Chem., 2017,8, 1353-1363
Article type
Paper

Surfactant-free RAFT emulsion polymerization using a novel biocompatible thermoresponsive polymer

N. P. Truong, J. F. Quinn, A. Anastasaki, M. Rolland, M. N. Vu, D. M. Haddleton, M. R. Whittaker and T. P. Davis, Polym. Chem., 2017, 8, 1353
DOI: 10.1039/C6PY02158A

Social activity

Search articles by author

Spotlight

Advertisements