Jump to main content
Jump to site search

Issue 32, 2017
Previous Article Next Article

Calcium carbide catalytically activated with tetra-n-butyl ammonium fluoride for Sonogashira cross coupling reactions

Author affiliations

Abstract

We report a novel method for the direct synthesis of mono- and bis-arylated alkynes utilizing catalytically activated CaC2 as the alkyne component. This fluoride-activated cross coupling reaction provides advantages over existing methods regarding operational simplicity, use of readily available starting materials, and low cost.

Graphical abstract: Calcium carbide catalytically activated with tetra-n-butyl ammonium fluoride for Sonogashira cross coupling reactions

Back to tab navigation

Supplementary files

Article information


Submitted
31 May 2017
Accepted
25 Jul 2017
First published
25 Jul 2017

Org. Biomol. Chem., 2017,15, 6800-6807
Article type
Paper

Calcium carbide catalytically activated with tetra-n-butyl ammonium fluoride for Sonogashira cross coupling reactions

A. Hosseini, A. Pilevar, E. Hogan, B. Mogwitz, A. S. Schulze and P. R. Schreiner, Org. Biomol. Chem., 2017, 15, 6800
DOI: 10.1039/C7OB01334E

Social activity

Search articles by author

Spotlight

Advertisements