Peng Fu and John B. MacMillan
Org. Biomol. Chem., 2017,15, 5275-5278
DOI:
10.1039/C7OB01178D,
Communication
Carpatizine (1), a new bridged oxazine derivative, was isolated from a marine-derived Streptomyces strain SNE-011. The structure was fully determined by spectroscopic analysis, ECD calculations and chemical methods. A plausible non-enzymatic reaction mechanism from daryamide D leading to carpatizine was presented, which was confirmed by chemical transformation.