Huijun Yuan, Lili Zhang, Zhantao Liu, Yang Liu, Jian Wang and Wenjun Li
Org. Biomol. Chem., 2017,15, 4286-4290
DOI:
10.1039/C7OB00906B,
Communication
A NHC-catalyzed 1,3-dipolar cycloaddition reaction of allyl ketones with azides has been developed. This strategy could generate 1,4,5-trisubstituted 1,2,3-triazoles in high yields and regioselectivities in the presence of a 20 mol% N-heterocyclic carbene catalyst. A broad substrate scope of this process is also presented.
