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Abstract | Cited by

A versatile copper(I)-catalyzed cascade multicomponent reaction strategy between readily available (Z)-3-iodoacrylic acids, terminal alkynes, and primary amines is reported, leading to a great diversity of complex heterocyclic backbones based on biorelevant indole/lactam scaffolds.

Graphical abstract: A tunable copper-catalyzed multicomponent reaction towards alkaloid-inspired indole/lactam polycycles

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