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Issue 15, 2017
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ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones

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Abstract

ipso-Annulation represents an attractive approach to synthesize a variety of spirocyclic compounds having a quaternary carbon center. Furthermore, these compounds also serve as a handy synthon for the construction of various complex molecules. This review presents various useful approaches for the intramolecular ipso-cyclization to afford a wide range of spirocyclohexadienones. In addition, the utility of spirocyclic compounds towards the synthesis of complex molecules is also included.

Graphical abstract: ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones

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Publication details

The article was received on 18 Feb 2017, accepted on 16 Mar 2017 and first published on 16 Mar 2017


Article type: Review Article
DOI: 10.1039/C7OB00405B
Citation: Org. Biomol. Chem., 2017,15, 3130-3151

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    ipso-Cyclization: an emerging tool for multifunctional spirocyclohexadienones

    C. R. Reddy, S. K. Prajapti, K. Warudikar, R. Ranjan and B. B. Rao, Org. Biomol. Chem., 2017, 15, 3130
    DOI: 10.1039/C7OB00405B

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