Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.

Issue 11, 2017
Previous Article Next Article

Isoafricanol synthase from Streptomyces malaysiensis

Author affiliations


Genome sequencing of Streptomyces malaysiensis DSM 4137 revealed the presence of four terpene cyclase genes, one of which was characterised as (+)-isoafricanol synthase. Its cyclisation mechanism was extensively studied using isotopically labelled precursors. Several enzymes with high homology that likely also function as (+)-isoafricanol synthases are encoded in a number of other genome sequenced streptomycetes.

Graphical abstract: Isoafricanol synthase from Streptomyces malaysiensis

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Jan 2017, accepted on 20 Feb 2017 and first published on 01 Mar 2017

Article type: Communication
DOI: 10.1039/C7OB00234C
Citation: Org. Biomol. Chem., 2017,15, 2353-2358

  •   Request permissions

    Isoafricanol synthase from Streptomyces malaysiensis

    P. Rabe, M. Samborskyy, P. F. Leadlay and J. S. Dickschat, Org. Biomol. Chem., 2017, 15, 2353
    DOI: 10.1039/C7OB00234C

Search articles by author