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Issue 19, 2017
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Recent progress in biomedical applications of persistent luminescence nanoparticles

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Abstract

Persistent luminescence nanoparticles (PLNPs) are an emerging group of promising luminescent materials that can remain luminescent after the excitation ceases. In the past decade, PLNPs with intriguing optical properties have been developed and their applications in biomedicine have been widely studied. Due to the ultra-long decay time of persistent luminescence, autofluorescence interference in biosensing and bioimaging can be efficiently eliminated. Moreover, PLNPs can remain luminescent for hours, making them valuable in bio-tracing. Also, persistent luminescence imaging can guide cancer therapy with a high signal-to-noise ratio (SNR) and superior sensitivity. Briefly, PLNPs are demonstrated to be a newly-emerging class of functional materials with unprecedented advantages in biomedicine. In this review, we summarized recent advances in the preparation of PLNPs and the applications of PLNPs in biosensing, bioimaging and cancer therapy.

Graphical abstract: Recent progress in biomedical applications of persistent luminescence nanoparticles

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Article information


Submitted
01 Mar 2017
Accepted
07 Apr 2017
First published
11 Apr 2017

Nanoscale, 2017,9, 6204-6218
Article type
Review Article

Recent progress in biomedical applications of persistent luminescence nanoparticles

J. Wang, Q. Ma, Y. Wang, H. Shen and Q. Yuan, Nanoscale, 2017, 9, 6204
DOI: 10.1039/C7NR01488K

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