Issue 17, 2017

Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

Abstract

A method is proposed for controlling the number of nanoparticles bound to cell membranes via RGDS peptide–integrin interactions. It consists of propelling nanoparticles bearing the peptides with enzymes (glucose oxidase), which disrupts biomolecular interactions as a function of the concentration of enzyme substrate (glucose).

Graphical abstract: Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

Supplementary files

Article information

Article type
Communication
Submitted
13 Jan 2017
Accepted
11 Apr 2017
First published
12 Apr 2017
This article is Open Access
Creative Commons BY license

Nanoscale, 2017,9, 5404-5407

Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

G. Rucinskaite, S. A. Thompson, S. Paterson and R. de la Rica, Nanoscale, 2017, 9, 5404 DOI: 10.1039/C7NR00298J

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