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Issue 12, 2017
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Appreciation of symmetry in natural product synthesis

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Covering: 2012 to June 2017

This review aims to show that complex natural product synthesis can be streamlined by taking advantage of molecular symmetry. Various strategies to construct molecules with either evident or hidden symmetry are illustrated. Insights regarding the origins and adjustments of these strategies as well as inspiring new methodological developments are deliberated. When a symmetric strategy fails, the corresponding reason is analysed and an alternative approach is briefly provided. Finally, the importance of exploiting molecular symmetry and future research directions are discussed.

Graphical abstract: Appreciation of symmetry in natural product synthesis

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Publication details

The article was received on 11 Sep 2017 and first published on 23 Nov 2017

Article type: Review Article
DOI: 10.1039/C7NP00045F
Citation: Nat. Prod. Rep., 2017,34, 1345-1358
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    Appreciation of symmetry in natural product synthesis

    W. Bai and X. Wang, Nat. Prod. Rep., 2017, 34, 1345
    DOI: 10.1039/C7NP00045F

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