Jump to main content
Jump to site search

Issue 2, 2017
Previous Article Next Article

Iron carbide nanoparticles: an innovative nanoplatform for biomedical applications

Author affiliations

Abstract

Iron carbide nanoparticles (ICNPs) are nano-intermetallic compounds that consist of iron and carbon. Benefiting from the magnetic and chemical activity of iron, and/or mechanical strength and chemical inertness of carbon, they have been widely applied in energetic and biomedical-related fields. Particularly in biomedicine, ICNPs have shown high colloidal stability and good performance in magnetic-dependent diagnosis and therapies such as magnetic resonance imaging (MRI) and magnetic hyperthermia (MH), due to their high magnetization and moderate coercivity. The carbon content protects ICNPs from oxidation and corrosion (ion release), which prolongs their life time and reduces their toxicity in physiological environments, and endows nanoparticles (NPs) with high performance in carbon-relevant theranostics as well. On this basis, ICNPs have great promise in multi-modal imaging or imaging-guided tumor-selective therapy to realize precise diagnoses with mild side effects. This paper aims to cover the state of the art applications of ICNPs in biomedicine, primarily including MRI, MH, magnetic targeting (MT), magnetic separation (MS), photothermal therapy (PTT) and photoacoustic tomography (PAT). The biocompatibility of ICNPs is also addressed.

Graphical abstract: Iron carbide nanoparticles: an innovative nanoplatform for biomedical applications

Back to tab navigation

Publication details

The article was received on 30 Sep 2016, accepted on 18 Nov 2016 and first published on 21 Nov 2016


Article type: Minireview
DOI: 10.1039/C6NH00173D
Citation: Nanoscale Horiz., 2017,2, 81-88

  •   Request permissions

    Iron carbide nanoparticles: an innovative nanoplatform for biomedical applications

    J. Yu, F. Chen, W. Gao, Y. Ju, X. Chu, S. Che, F. Sheng and Y. Hou, Nanoscale Horiz., 2017, 2, 81
    DOI: 10.1039/C6NH00173D

Search articles by author

Spotlight

Advertisements