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Issue 6, 2017
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Liquid metal enabled microfluidics

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Several gallium-based liquid metal alloys are liquid at room temperature. As ‘liquid’, such alloys have a low viscosity and a high surface tension while as ‘metal’, they have high thermal and electrical conductivities, similar to mercury. However, unlike mercury, these liquid metal alloys have low toxicity and a negligible vapor pressure, rendering them much safer. In comparison to mercury, the distinguishing feature of these alloys is the rapid formation of a self-limiting atomically thin layer of gallium oxide over their surface when exposed to oxygen. This oxide layer changes many physical and chemical properties of gallium alloys, including their interfacial and rheological properties, which can be employed and modulated for various applications in microfluidics. Injecting liquid metal into microfluidic structures has been extensively used to pattern and encapsulate highly deformable and reconfigurable electronic devices including electrodes, sensors, antennas, and interconnects. Likewise, the unique features of liquid metals have been employed for fabricating miniaturized microfluidic components including pumps, valves, heaters, and electrodes. In this review, we discuss liquid metal enabled microfluidic components, and highlight their desirable attributes including simple fabrication, facile integration, stretchability, reconfigurability, and low power consumption, with promising applications for highly integrated microfluidic systems.

Graphical abstract: Liquid metal enabled microfluidics

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Article information

14 Jan 2017
10 Feb 2017
First published
14 Feb 2017

Lab Chip, 2017,17, 974-993
Article type
Tutorial Review

Liquid metal enabled microfluidics

K. Khoshmanesh, S. Tang, J. Y. Zhu, S. Schaefer, A. Mitchell, K. Kalantar-zadeh and M. D. Dickey, Lab Chip, 2017, 17, 974
DOI: 10.1039/C7LC00046D

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