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Issue 33, 2017
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A Perspective – can copper complexes be developed as a novel class of therapeutics?

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Abstract

Although copper–ligand complexes appear to be promising as a new class of therapeutics, other than the family of copper(II) coordination compounds referred to as casiopeínas these compounds have yet to reach the clinic for human use. The pharmaceutical challenges associated with developing copper-based therapeutics will be presented in this article along with a discussion of the potential for high-throughput chemistry, computer-aided drug design, and nanotechnology to address the development of this important class of drug candidates.

Graphical abstract: A Perspective – can copper complexes be developed as a novel class of therapeutics?

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Article information


Submitted
29 May 2017
Accepted
04 Jul 2017
First published
04 Jul 2017

Dalton Trans., 2017,46, 10758-10773
Article type
Perspective

A Perspective – can copper complexes be developed as a novel class of therapeutics?

M. Wehbe, A. W. Y. Leung, M. J. Abrams, C. Orvig and M. B. Bally, Dalton Trans., 2017, 46, 10758
DOI: 10.1039/C7DT01955F

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