Carboberyllation: addition of organoberyllium species to alkenes and alkynes. A comparison with carboboration
The potential for carbometallation reactions between organoberyllium and model alkenes and alkynes has been investigated in a computational study. Results indicate that barriers for carbometallation reactions between BeR2 and alkynes are as low as 100 kJ mol−1, and much lower than corresponding reactions with MgR2. In contrast to carboboration reactions with BR3, with organoberyllium 1,2-addition is favoured over 1,1-addition. It is concluded that carbometallation reactions with beryllium are likely feasible, and that the reaction between BePh2 and alkynes provides the best opportunity for the first experimental observation of carboberyllation.