Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 2, 2018
Previous Article Next Article

Covalent post-assembly modification in metallosupramolecular chemistry

Author affiliations

Abstract

A growing variety of covalent reactions have been employed to achieve the post-assembly modification (PAM) of self-assembled metallosupramolecular complexes. Covalent PAM enables the late-stage derivatisation of pre-assembled parent complexes in a modular fashion, thus expanding the chemical space available for supramolecular synthesis. The oldest and most widespread implementation of covalent PAM is in metal-preorganised covalent synthesis. Recent work, however, has broadened the scope of covalent PAM to include: protocols for efficiently grafting new functionalities onto supramolecular architectures, reactions that permanently ‘lock-down’ metastable complexes, and covalent bond-forming stimuli that trigger controlled structural transformations between distinct supramolecular species. This review highlights key examples of each of these distinct kinds of covalent PAM in metallosupramolecular chemistry, before providing a perspective upon future challenges and opportunities.

Graphical abstract: Covalent post-assembly modification in metallosupramolecular chemistry

Back to tab navigation

Article information


Submitted
19 Sep 2017
First published
16 Nov 2017

Chem. Soc. Rev., 2018,47, 626-644
Article type
Review Article

Covalent post-assembly modification in metallosupramolecular chemistry

D. A. Roberts, B. S. Pilgrim and J. R. Nitschke, Chem. Soc. Rev., 2018, 47, 626
DOI: 10.1039/C6CS00907G

Social activity

Search articles by author

Spotlight

Advertisements