Jump to main content
Jump to site search

Issue 36, 2017

Quantitative probing of subtle interactions among H-bonds in alpha hydroxy carboxylic acid complexes

Author affiliations

Abstract

Hydrogen (H) bonds are of fundamental importance in a wide range of molecular sciences. While the study of two-center H-bonding A⋯H is well advanced, much remains to be learned in a quantitative and definitive manner for complexes with multiple H-bonds. Exemplary cases are in the category of alpha hydroxy carboxylic acids, i.e., the complexes of glycolic acid with water and formic acid. In glycolic acid, an intramolecular H-bond forms between the carboxyl group and the alpha OH group. The alpha OH stretching frequency may be affected upon complexing with water or formic acid. Direct study of glycolic acid complexes is unfortunately very difficult. However, an aromatic analogue, 9-hydroxy-9-fluorene carboxylic acid (9HFCA), permits detailed and accurate gas phase spectroscopic studies. Since computational analysis establishes that H-bonding is very similar from glycolic acid complexes to 9HFCA complexes, direct studies on 9HFCA complexes by laser spectroscopy also deduce new and subtle information for glycolic acid complexes in terms of molecular structures, binding strength, and collective effects of multiple H-bonds associated with anti-cooperativity and cooperativity.

Graphical abstract: Quantitative probing of subtle interactions among H-bonds in alpha hydroxy carboxylic acid complexes

Article information


Submitted
12 Jun 2017
Accepted
06 Jul 2017
First published
06 Jul 2017

Phys. Chem. Chem. Phys., 2017,19, 24399-24411
Article type
Perspective

Quantitative probing of subtle interactions among H-bonds in alpha hydroxy carboxylic acid complexes

Q. Gu, P. Su, Y. Xia, Z. Yang, C. O. Trindle and J. L. Knee, Phys. Chem. Chem. Phys., 2017, 19, 24399 DOI: 10.1039/C7CP03917D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements