Issue 97, 2017
From the journal:

Chemical Communications

Physiological pH-dependent gelation for 3D printing based on the phase separation of gelatin and oxidized dextran†

Zengmin Du,a   Ningfeng Li,b   Yujie Hua,b   Yong Shi,c   Chunyan Bao, ORCID logo b   Hongbo Zhang,c   Yi Yang,a   Qiuning Lin ORCID logo *b  and  Linyong Zhu ORCID logo b  

* Corresponding authors

a State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130# Meilong Road, Shanghai, China

b Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130# Meilong Road, Shanghai, China
E-mail: qiuninglin@ecust.edu.cn

c School of Mechanics, East China University of Science and Technology, 130# Meilong Road, Shanghai, China

Abstract

An extrudable hydrogel with a tunable gelation time under physiological pH ranges based on the phase separation of gelatin and oxidized dextran was demonstrated. We envision that the easy handing properties of this hydrogel combined with thermosensitive physical gelation and postponed chemical reinforcing will provide a platform for 3D bioprinting applications.

Graphical abstract: Physiological pH-dependent gelation for 3D printing based on the phase separation of gelatin and oxidized dextran

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Article information

DOI
https://doi.org/10.1039/C7CC08225H
Article type
Communication
Submitted
25 Oct 2017
Accepted
09 Nov 2017
First published
09 Nov 2017

Chem. Commun., 2017,53, 13023-13026

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Physiological pH-dependent gelation for 3D printing based on the phase separation of gelatin and oxidized dextran

Z. Du, N. Li, Y. Hua, Y. Shi, C. Bao, H. Zhang, Y. Yang, Q. Lin and L. Zhu, Chem. Commun., 2017, 53, 13023 DOI: 10.1039/C7CC08225H

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