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Issue 97, 2017
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Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

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Abstract

Photodynamic therapy (PDT) requires a photosensitizer, light, and oxygen to induce cell death. The majority of efforts to advance PDT focus only on the first two components. Here, we employ perfluorocarbon nanoemulsions to simultaneously deliver oxygen and a photosensitizer. We find that the implementation of fluorous soluble photosensitizers enhances the efficacy of PDT.

Graphical abstract: Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

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Publication details

The article was received on 08 Sep 2017, accepted on 13 Nov 2017 and first published on 22 Nov 2017


Article type: Communication
DOI: 10.1039/C7CC07038A
Chem. Commun., 2017,53, 13043-13046

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    Fluorous photosensitizers enhance photodynamic therapy with perfluorocarbon nanoemulsions

    R. A. Day, D. A. Estabrook, J. K. Logan and E. M. Sletten, Chem. Commun., 2017, 53, 13043
    DOI: 10.1039/C7CC07038A

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