Issue 85, 2017
From the journal:

Chemical Communications

Thermally-induced lateral assembly of a PEG-containing amphiphile triggering vesicle budding†

Rui Li,a   Takahiro Muraoka ORCID logo *bc  and  Kazushi Kinbara ORCID logo *ab  

* Corresponding authors

a Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Japan

b Department of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Japan
E-mail: kkinbara@bio.titech.ac.jp

c PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama, Japan

Abstract

A macrocyclic amphiphile consisting of a thermo-responsive octaethylene glycol chain with hydrophobic aromatic and aliphatic units undergoes lateral self-assembly in a liquid-disordered-state phospholipid bilayer membrane upon heating, which further leads to vesicle budding.

Graphical abstract: Thermally-induced lateral assembly of a PEG-containing amphiphile triggering vesicle budding

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Article information

DOI
https://doi.org/10.1039/C7CC06489F
Article type
Communication
Submitted
18 Aug 2017
Accepted
03 Oct 2017
First published
03 Oct 2017

Chem. Commun., 2017,53, 11662-11665

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Thermally-induced lateral assembly of a PEG-containing amphiphile triggering vesicle budding

R. Li, T. Muraoka and K. Kinbara, Chem. Commun., 2017, 53, 11662 DOI: 10.1039/C7CC06489F

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