Nikki L. Sloan, Sajinder K. Luthra, Graeme McRobbie, Sally L. Pimlott and Andrew Sutherland
Chem. Commun., 2017,53, 11008-11011
DOI:
10.1039/C7CC06211G,
Communication
An operationally simple, one-pot, two-step tandem procedure that allows the incorporation of radioactive iodine into aryl amines via stable diazonium salts is described. The mild conditions are tolerant of various functional groups and substitution patterns, allowing late-stage, rapid access to a wide range of 125I-labelled aryl compounds and SPECT radiotracers.