Issue 76, 2017

Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

Abstract

The real-time monitoring of nitric oxide (NO) at the subcellular level is still a great challenge. To attain this goal, we developed a fast and selective near-infrared (NIR) fluorescent probe for the targeted tracing of endogenous NO. This probe possesses vital features for the real-time detection of intracellular NO including a significant turn-on NIR response, high specificity, and a fast response by a controlled photoinduced electron transfer (PET) process, which is applicable to the real-time monitoring of endogenous NO in mitochondria.

Graphical abstract: Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

Supplementary files

Article information

Article type
Communication
Submitted
31 Jul 2017
Accepted
30 Aug 2017
First published
31 Aug 2017

Chem. Commun., 2017,53, 10520-10523

Rational design of a fast and selective near-infrared fluorescent probe for targeted monitoring of endogenous nitric oxide

J. Tang, Z. Guo, Y. Zhang, B. Bai and W. Zhu, Chem. Commun., 2017, 53, 10520 DOI: 10.1039/C7CC05971J

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