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Issue 79, 2017

α-Helical peptide vesicles with chiral membranes as enantioselective nanoreactors

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Abstract

We report peptide vesicles with chiral membranes as enantioselective nanoreactors. The peptide vesicles are able to selectively encapsulate only a single enantiomer from a racemic mixture solution through preferential diffusion across the membranes. Notably, the confined space of the vesicle acts as an enantioselective nanoreactor for the encapsulated enantiomer which undergoes further chemical transformations to yield a highly enantiopure product.

Graphical abstract: α-Helical peptide vesicles with chiral membranes as enantioselective nanoreactors

Supplementary files

Article information


Submitted
28 Jul 2017
Accepted
13 Sep 2017
First published
13 Sep 2017

Chem. Commun., 2017,53, 10958-10961
Article type
Communication

α-Helical peptide vesicles with chiral membranes as enantioselective nanoreactors

X. Chen, Y. Wang, H. Wang, Y. Kim and M. Lee, Chem. Commun., 2017, 53, 10958 DOI: 10.1039/C7CC05869A

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