Issue 62, 2017
From the journal:

Chemical Communications

Instrument-free visual detection of tetracycline on an autocatalytic DNA machine using a caged G-quadruplex as the signal reporter†

Junhua Chen, ORCID logo *a   Shu Chena  and  Fengling Lia  

* Corresponding authors

a Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and Management, Guangdong Institute of Eco-environmental Science & Technology, Guangzhou 510650, China
E-mail: 222chenjunhua@163.com, jhchen@soil.gd.cn

Abstract

An instrument-free visual biosensor for the amplified detection of tetracycline has been successfully constructed using an autocatalytic DNA machine as the signal amplifier and a caged G-quadruplex as the signal reporter. The assay is ultrasensitive, enabling the visual detection of trace levels of tetracycline as low as 1 pM without instrumentation.

Graphical abstract: Instrument-free visual detection of tetracycline on an autocatalytic DNA machine using a caged G-quadruplex as the signal reporter

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Article information

DOI
https://doi.org/10.1039/C7CC04083K
Article type
Communication
Submitted
26 May 2017
Accepted
11 Jul 2017
First published
11 Jul 2017

Chem. Commun., 2017,53, 8743-8746

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Instrument-free visual detection of tetracycline on an autocatalytic DNA machine using a caged G-quadruplex as the signal reporter

J. Chen, S. Chen and F. Li, Chem. Commun., 2017, 53, 8743 DOI: 10.1039/C7CC04083K

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