Jump to main content
Jump to site search

Issue 60, 2017
Previous Article Next Article

Thiol-reactive (co)polymer scaffolds comprising organic arsenical acrylamides

Author affiliations

Abstract

Novel, well-defined organic arsenical homopolymers (Đ = 1.10–1.40) have been synthesised via RAFT polymerisation. Copolymerisation of the As-functional monomer with dimethylacrylamide yielded non-toxic polymer scaffolds (Đ ≈ 1.10) that could be manipulated in response to pH and undergo sequential reduction and substitution in the presence of thiols including cysteine and glutathione.

Graphical abstract: Thiol-reactive (co)polymer scaffolds comprising organic arsenical acrylamides

Back to tab navigation

Supplementary files

Article information


Submitted
19 May 2017
Accepted
06 Jul 2017
First published
06 Jul 2017

Chem. Commun., 2017,53, 8447-8450
Article type
Communication

Thiol-reactive (co)polymer scaffolds comprising organic arsenical acrylamides

C. Footman, P. A. J. M. de Jongh, J. Tanaka, R. Peltier, K. Kempe, T. P. Davis and P. Wilson, Chem. Commun., 2017, 53, 8447
DOI: 10.1039/C7CC03880A

Social activity

Search articles by author

Spotlight

Advertisements