Issue 60, 2017
From the journal:

Chemical Communications

Electrochemical synthesis of phthalides via anodic activation of aromatic carboxylic acids†

Davit Hayrapetyan,b   Viacheslav Shkepu,b   Olzhas T. Seilkhanov,c   Zhaisan Zhanabilb  and  Kevin Lam ORCID logo *ab  

* Corresponding authors

a Department of Pharmaceutical, Chemical and Environmental Sciences, Faculty of Engineering and Science, University of Greenwich, Central Avenue, Chatham Maritime, Chatham, Kent ME4 4TB, UK
E-mail: k.lam@greenwich.ac.uk

b Department of Chemistry, Nazarbayev University, 53 Kabanbay Batyr Avenue, 010 000 Astana, Republic of Kazakhstan
E-mail: kevin.lam@nu.edu.kz

c Laboratory of Engineering Profile NMR Spectroscopy Sh. Ualikhanov Kokshetau State University, Abay Str., 76, 020000 Kokshetau, Republic of Kazakhstan

Abstract

A novel electrochemical synthesis of phthalides was successfully developed using anodically generated aroyloxy radicals in combination with aliphatic carboxylic acid as cheap and readily available alkylating agent precursors.

Graphical abstract: Electrochemical synthesis of phthalides via anodic activation of aromatic carboxylic acids

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Article information

DOI
https://doi.org/10.1039/C7CC03669H
Article type
Communication
Submitted
11 May 2017
Accepted
05 Jul 2017
First published
06 Jul 2017

Chem. Commun., 2017,53, 8451-8454

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Electrochemical synthesis of phthalides via anodic activation of aromatic carboxylic acids

D. Hayrapetyan, V. Shkepu, O. T. Seilkhanov, Z. Zhanabil and K. Lam, Chem. Commun., 2017, 53, 8451 DOI: 10.1039/C7CC03669H

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