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Issue 52, 2017
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Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

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Abstract

Bismuth subgallate has been used in wound and gastrointestinal therapy for over a century. The combination of continuous rotation electron diffraction and sample cooling finally revealed its structure as a coordination polymer. The structure provides insight regarding its formula, poor solubility, acid resistance and previously unreported gas sorption properties.

Graphical abstract: Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

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Supplementary files

Article information


Submitted
25 Apr 2017
Accepted
07 Jun 2017
First published
07 Jun 2017

This article is Open Access

Chem. Commun., 2017,53, 7018-7021
Article type
Communication

Elucidation of the elusive structure and formula of the active pharmaceutical ingredient bismuth subgallate by continuous rotation electron diffraction

Y. Wang, S. Takki, O. Cheung, H. Xu, W. Wan, L. Öhrström and A. K. Inge, Chem. Commun., 2017, 53, 7018
DOI: 10.1039/C7CC03180G

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