S. R. Ellis, J. Soltwisch, M. R. L. Paine, K. Dreisewerd and R. M. A. Heeren
Chem. Commun., 2017,53, 7246-7249
DOI:
10.1039/C7CC02325A,
Communication
Coupling laser post-ionisation with a high resolving power MALDI Orbitrap mass spectrometer has realised an up to ∼100-fold increase in the sensitivity and enhanced the chemical coverage for MALDI-MS imaging of lipids relative to conventional MALDI. This could constitute a major breakthrough for biomedical research.