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Issue 46, 2017
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Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging

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Abstract

A novel nanoparticle-based imaging strategy is introduced that couples biocompatible organic nanoparticles and stimulated Raman scattering (SRS) microscopy. Polymer nanoparticles with vibrational labels incorporated were readily prepared for multi-color SRS imaging with excellent photo-stability. The Raman-active polymer dots are nontoxic, rapidly enter various cell types, and are applied in multiplexed cell-type sorting.

Graphical abstract: Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging

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Supplementary files

Article information


Submitted
10 Mar 2017
Accepted
25 Apr 2017
First published
25 Apr 2017

Chem. Commun., 2017,53, 6187-6190
Article type
Communication

Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging

F. Hu, S. D. Brucks, T. H. Lambert, L. M. Campos and W. Min, Chem. Commun., 2017, 53, 6187
DOI: 10.1039/C7CC01860F

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