Issue 54, 2017
From the journal:

Chemical Communications

Double duplex invasion of DNA induced by ultrafast photo-cross-linking using 3-cyanovinylcarbazole for antigene methods†

Shigetaka Nakamura, ORCID logo a   Hayato Kawabataa  and  Kenzo Fujimoto*a  

* Corresponding authors

a Department of Advanced Science and Technology, Japan Advanced Institute Science and Technology, Asahi-dai, 1-1, Nomi, Ishikawa, Japan
E-mail: kenzo@jaist.ac.jp

Abstract

In the creation of double duplex formation with genomic DNA, the probe must be able to invade and hybridize to the duplex DNA. We designed new photoresponsive probes containing CNVK and CNU; these probes have a high double-duplex invasion capability upon photoirradiation.

Graphical abstract: Double duplex invasion of DNA induced by ultrafast photo-cross-linking using 3-cyanovinylcarbazole for antigene methods

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Article information

DOI
https://doi.org/10.1039/C7CC01746D
Article type
Communication
Submitted
07 Mar 2017
Accepted
12 Jun 2017
First published
15 Jun 2017

Chem. Commun., 2017,53, 7616-7619

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Double duplex invasion of DNA induced by ultrafast photo-cross-linking using 3-cyanovinylcarbazole for antigene methods

S. Nakamura, H. Kawabata and K. Fujimoto, Chem. Commun., 2017, 53, 7616 DOI: 10.1039/C7CC01746D

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