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Issue 26, 2017
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Room-temperature synthesis of core–shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

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Abstract

Core–shell structured magnetic covalent organic frameworks (Fe3O4@COFs) were synthesized via a facile approach at room temperature. Combining the advantages of high porosity, magnetic responsiveness, chemical stability and selectivity, Fe3O4@COFs can serve as an ideal absorbent for the highly efficient enrichment of peptides and the simultaneous exclusion of proteins from complex biological samples.

Graphical abstract: Room-temperature synthesis of core–shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

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Article information


Submitted
18 Jan 2017
Accepted
09 Mar 2017
First published
09 Mar 2017

Chem. Commun., 2017,53, 3649-3652
Article type
Communication

Room-temperature synthesis of core–shell structured magnetic covalent organic frameworks for efficient enrichment of peptides and simultaneous exclusion of proteins

G. Lin, C. Gao, Q. Zheng, Z. Lei, H. Geng, Z. Lin, H. Yang and Z. Cai, Chem. Commun., 2017, 53, 3649
DOI: 10.1039/C7CC00482F

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