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Issue 21, 2017
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Reversible DNA micro-patterning using the fluorous effect

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Abstract

We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.

Graphical abstract: Reversible DNA micro-patterning using the fluorous effect

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Supplementary files

Article information


Submitted
12 Jan 2017
Accepted
15 Feb 2017
First published
23 Feb 2017

This article is Open Access

Chem. Commun., 2017,53, 3094-3097
Article type
Communication

Reversible DNA micro-patterning using the fluorous effect

G. E. Flynn, J. M. Withers, G. Macias, J. R. Sperling, S. L. Henry, J. M. Cooper, G. A. Burley and A. W. Clark, Chem. Commun., 2017, 53, 3094
DOI: 10.1039/C7CC00288B

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